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Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer

BACKGROUND: Reovirus type 3 Dearing (T3D) has demonstrated oncolytic activity in vitro, in in vivo murine models and in early clinical trials. However the true potential of oncolytic viruses may only be realized fully in combination with other modalities such as chemotherapy, targeted therapy and ra...

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Detalles Bibliográficos
Autores principales: Heinemann, Lucy, Simpson, Guy R, Boxall, Angela, Kottke, Timothy, Relph, Kate L, Vile, Richard, Melcher, Alan, Prestwich, Robin, Harrington, Kevin J, Morgan, Richard, Pandha, Hardev S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129324/
https://www.ncbi.nlm.nih.gov/pubmed/21645351
http://dx.doi.org/10.1186/1471-2407-11-221