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Estradiol-Treated Female Mice as Surrogate Hosts for Neisseria gonorrhoeae Genital Tract Infections

Historically, animal modeling of gonorrhea has been hampered by the exclusive adaptation of Neisseria gonorrhoeae to humans. Genital tract infection can be established in female mice that are treated with 17β-estradiol, however, and many features of experimental murine infection mimic human infectio...

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Detalles Bibliográficos
Autores principales: Jerse, Ann E., Wu, Hong, Packiam, Mathanraj, Vonck, Rachel A., Begum, Afrin A., Garvin, Lotisha E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129519/
https://www.ncbi.nlm.nih.gov/pubmed/21747807
http://dx.doi.org/10.3389/fmicb.2011.00107