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Estimating equations for biomarker based exposure estimation under non-steady-state conditions
Unrealistic steady-state assumptions are often used to estimate toxicant exposure rates from biomarkers. A biomarker may instead be modeled as a weighted sum of historical time-varying exposures. Estimating equations are derived for a zero-inflated gamma distribution for daily exposures with a known...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129579/ https://www.ncbi.nlm.nih.gov/pubmed/21668990 http://dx.doi.org/10.1186/1476-069X-10-57 |