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Estimating equations for biomarker based exposure estimation under non-steady-state conditions

Unrealistic steady-state assumptions are often used to estimate toxicant exposure rates from biomarkers. A biomarker may instead be modeled as a weighted sum of historical time-varying exposures. Estimating equations are derived for a zero-inflated gamma distribution for daily exposures with a known...

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Detalles Bibliográficos
Autores principales: Bartell, Scott M, Johnson, Wesley O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129579/
https://www.ncbi.nlm.nih.gov/pubmed/21668990
http://dx.doi.org/10.1186/1476-069X-10-57