hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets

The analysis of contiguous homozygosity (runs of homozygous loci) in human genotyping datasets is critical in the search for causal disease variants in monogenic disorders, studies of population history and the identification of targets of natural selection. Here, we report methods for extracting ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Todd A, Niimura, Yoshihito, Tanaka, Hiroshi, Nakamura, Yusuke, Tsunoda, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129671/
https://www.ncbi.nlm.nih.gov/pubmed/21396103
http://dx.doi.org/10.1186/gb-2011-12-3-r21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129671/
https://www.ncbi.nlm.nih.gov/pubmed/21396103
http://dx.doi.org/10.1186/gb-2011-12-3-r21

Ejemplares similares