Frequency of genetic polymorphisms of PXR gene in the Brazilian population

INTRODUCTION: PXR polymorphisms have been implicated in modulating CYP3A4 and PXR expression, potentially accounting for interindividual differences in drug metabolism. The prevalence of PXR polymorphisms varies among ethnic groups and data on the allelic distribution in the highly mixed Brazilian p...

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Detalles Bibliográficos
Autores principales: Moreira, Ricardo P P, Jorge, Alexander A L, Mendonca, Berenice B, Bachega, Tânia A S S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129971/
https://www.ncbi.nlm.nih.gov/pubmed/21808872
http://dx.doi.org/10.1590/S1807-59322011000600020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129971/
https://www.ncbi.nlm.nih.gov/pubmed/21808872
http://dx.doi.org/10.1590/S1807-59322011000600020

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