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VLDL Hydrolysis by Hepatic Lipase Regulates PPARδ Transcriptional Responses

BACKGROUND: PPARs (α,γ,δ) are a family of ligand-activated transcription factors that regulate energy balance, including lipid metabolism. Despite these critical functions, the integration between specific pathways of lipid metabolism and distinct PPAR responses remains obscure. Previous work has re...

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Detalles Bibliográficos
Autores principales: Brown, Jonathan D., Oligino, Eric, Rader, Daniel J., Saghatelian, Alan, Plutzky, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130023/
https://www.ncbi.nlm.nih.gov/pubmed/21750705
http://dx.doi.org/10.1371/journal.pone.0021209