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Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

BACKGROUND: In hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and disease progression remains unclear. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Lamb, John R., Zhang, Chunsheng, Xie, Tao, Wang, Kai, Zhang, Bin, Hao, Ke, Chudin, Eugene, Fraser, Hunter B., Millstein, Joshua, Ferguson, Mark, Suver, Christine, Ivanovska, Irena, Scott, Martin, Philippar, Ulrike, Bansal, Dimple, Zhang, Zhan, Burchard, Julja, Smith, Ryan, Greenawalt, Danielle, Cleary, Michele, Derry, Jonathan, Loboda, Andrey, Watters, James, Poon, Ronnie T. P., Fan, Sheung T., Yeung, Chun, Lee, Nikki P. Y., Guinney, Justin, Molony, Cliona, Emilsson, Valur, Buser-Doepner, Carolyn, Zhu, Jun, Friend, Stephen, Mao, Mao, Shaw, Peter M., Dai, Hongyue, Luk, John M., Schadt, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130029/
https://www.ncbi.nlm.nih.gov/pubmed/21750698
http://dx.doi.org/10.1371/journal.pone.0020090