Cargando…

mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation

We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, James, Yaba, Aylin, Kasiman, Corinna, Thomson, Travis, Johnson, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130037/
https://www.ncbi.nlm.nih.gov/pubmed/21750711
http://dx.doi.org/10.1371/journal.pone.0021415