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mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation
We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of...
Autores principales: | Yu, James, Yaba, Aylin, Kasiman, Corinna, Thomson, Travis, Johnson, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130037/ https://www.ncbi.nlm.nih.gov/pubmed/21750711 http://dx.doi.org/10.1371/journal.pone.0021415 |
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