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Loss of PTB or Negative Regulation of Notch mRNA Reveals Distinct Zones of Notch and Actin Protein Accumulation in Drosophila Embryo

Polypyrimidine Tract Binding (PTB) protein is a regulator of mRNA processing and translation. Genetic screens and studies of wing and bristle development during the post-embryonic stages of Drosophila suggest that it is a negative regulator of the Notch pathway. How PTB regulates the Notch pathway i...

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Detalles Bibliográficos
Autores principales: Wesley, Cedric S., Guo, Heng, Chaudhry, Kanita A., Thali, Markus J., Yin, Jerry C., Clason, Todd, Wesley, Umadevi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130057/
https://www.ncbi.nlm.nih.gov/pubmed/21750738
http://dx.doi.org/10.1371/journal.pone.0021876