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Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation

Canonical Wnt-signalling has been implicated in mouse and human embryonic stem cell (ESC) maintenance, however its requirement is controversial. β-catenin is the key component in this highly conserved Wnt pathway, acting as a transcriptional transactivator. Yet, β-catenin has additional roles at the...

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Detalles Bibliográficos
Autores principales:	Lyashenko, Natalia, Winter, Markus, Migliorini, Domenico, Biechele, Travis, Moon, Randall T., Hartmann, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130149/ https://www.ncbi.nlm.nih.gov/pubmed/21685890 http://dx.doi.org/10.1038/ncb2260

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