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Actin and myosin contribute to mammalian mitochondrial DNA maintenance

Mitochondrial DNA maintenance and segregation are dependent on the actin cytoskeleton in budding yeast. We found two cytoskeletal proteins among six proteins tightly associated with rat liver mitochondrial DNA: non-muscle myosin heavy chain IIA and β-actin. In human cells, transient gene silencing o...

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Detalles Bibliográficos
Autores principales: Reyes, A., He, J., Mao, C. C., Bailey, L. J., Di Re, M., Sembongi, H., Kazak, L., Dzionek, K., Holmes, J. B., Cluett, T. J., Harbour, M. E., Fearnley, I. M., Crouch, R. J., Conti, M. A., Adelstein, R. S., Walker, J. E., Holt, I. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130256/
https://www.ncbi.nlm.nih.gov/pubmed/21398640
http://dx.doi.org/10.1093/nar/gkr052