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Rapid binding and release of Hfq from ternary complexes during RNA annealing

The Sm protein Hfq binds small non-coding RNA (sRNAs) in bacteria and facilitates their base pairing with mRNA targets. Molecular beacons and a 16 nt RNA derived from the Hfq binding site in DsrA sRNA were used to investigate how Hfq accelerates base pairing between complementary strands of RNA. Sto...

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Detalles Bibliográficos
Autores principales: Hopkins, Julia F., Panja, Subrata, Woodson, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130257/
https://www.ncbi.nlm.nih.gov/pubmed/21378124
http://dx.doi.org/10.1093/nar/gkr062