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Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells

Sam68 plays an essential role in mouse spermatogenesis and male fertility. Herein, we report an interaction between Sam68 and the phosphorylated forms of the RNA polymerase II (RNAPII) in meiotic spermatocytes. RNase treatment decreased but did not abolish the interaction, consistently with in vitro...

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Detalles Bibliográficos
Autores principales: Paronetto, Maria Paola, Messina, Valeria, Barchi, Marco, Geremia, Raffaele, Richard, Stéphane, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130265/
https://www.ncbi.nlm.nih.gov/pubmed/21355037
http://dx.doi.org/10.1093/nar/gkr085