Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression

Here, we report that the untreated rabbit reticulocyte lysate contains over 300 different endogenous microRNAs together with the major components of the RNA-induced silencing complex and thus can be used as a model in vitro system to study the effects of microRNAs on gene expression. By using this s...

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Detalles Bibliográficos
Autores principales: Ricci, Emiliano P., Limousin, Taran, Soto-Rifo, Ricardo, Allison, Rachel, Pöyry, Tuija, Decimo, Didier, Jackson, Richard J., Ohlmann, Théophile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130266/
https://www.ncbi.nlm.nih.gov/pubmed/21385827
http://dx.doi.org/10.1093/nar/gkr086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130266/
https://www.ncbi.nlm.nih.gov/pubmed/21385827
http://dx.doi.org/10.1093/nar/gkr086

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