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Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression
Here, we report that the untreated rabbit reticulocyte lysate contains over 300 different endogenous microRNAs together with the major components of the RNA-induced silencing complex and thus can be used as a model in vitro system to study the effects of microRNAs on gene expression. By using this s...
Autores principales: | Ricci, Emiliano P., Limousin, Taran, Soto-Rifo, Ricardo, Allison, Rachel, Pöyry, Tuija, Decimo, Didier, Jackson, Richard J., Ohlmann, Théophile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130266/ https://www.ncbi.nlm.nih.gov/pubmed/21385827 http://dx.doi.org/10.1093/nar/gkr086 |
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