Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain

Lens epithelium-derived growth factor (LEDGF) or p75 is a co-activator of general transcription and also involved in insertion of human immunodeficiency virus type I (HIV-1) cDNA into host cell genome, which occurs preferentially to active transcription units. These phenomena may share an underlying...

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Detalles Bibliográficos
Autores principales: Tsutsui, Kimiko M., Sano, Kuniaki, Hosoya, Osamu, Miyamoto, Tadashi, Tsutsui, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130267/
https://www.ncbi.nlm.nih.gov/pubmed/21345933
http://dx.doi.org/10.1093/nar/gkr088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130267/
https://www.ncbi.nlm.nih.gov/pubmed/21345933
http://dx.doi.org/10.1093/nar/gkr088

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