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Guanine radical chemistry reveals the effect of thermal fluctuations in gene promoter regions

DNA is not the static entity that structural pictures suggest. It has been longly known that it ‘breathes’ and fluctuates by local opening of the bases. Here we show that the effect of structural fluctuations, exhibited by AT-rich low stability regions present in some common transcription initiation...

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Detalles Bibliográficos
Autores principales: Cuesta-López, Santiago, Menoni, Hervé, Angelov, Dimitar, Peyrard, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130270/
https://www.ncbi.nlm.nih.gov/pubmed/21398632
http://dx.doi.org/10.1093/nar/gkr096