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Guanine radical chemistry reveals the effect of thermal fluctuations in gene promoter regions
DNA is not the static entity that structural pictures suggest. It has been longly known that it ‘breathes’ and fluctuates by local opening of the bases. Here we show that the effect of structural fluctuations, exhibited by AT-rich low stability regions present in some common transcription initiation...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130270/ https://www.ncbi.nlm.nih.gov/pubmed/21398632 http://dx.doi.org/10.1093/nar/gkr096 |