Cargando…
Guanine radical chemistry reveals the effect of thermal fluctuations in gene promoter regions
DNA is not the static entity that structural pictures suggest. It has been longly known that it ‘breathes’ and fluctuates by local opening of the bases. Here we show that the effect of structural fluctuations, exhibited by AT-rich low stability regions present in some common transcription initiation...
Autores principales: | Cuesta-López, Santiago, Menoni, Hervé, Angelov, Dimitar, Peyrard, Michel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130270/ https://www.ncbi.nlm.nih.gov/pubmed/21398632 http://dx.doi.org/10.1093/nar/gkr096 |
Ejemplares similares
-
Guanine base stacking in G-quadruplex nucleic acids
por: Lech, Christopher Jacques, et al.
Publicado: (2013) -
Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends
por: Boopathi, Ramachandran, et al.
Publicado: (2020) -
Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide
por: Troisi, Romualdo, et al.
Publicado: (2023) -
Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context
por: Rodríguez, Fabián A., et al.
Publicado: (2007) -
Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes
por: Gros, Julien, et al.
Publicado: (2007)