Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro

Upon endoplasmic reticulum (ER) stress, mammalian cells induce the synthesis of a transcriptional activator XBP1s to alleviate the stress. Under unstressed conditions, the messenger RNA (mRNA) for XBP1s exists in the cytosol as an unspliced precursor form, XBP1u mRNA. Thus, its intron must be remove...

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Detalles Bibliográficos
Autores principales: Shinya, Sayoko, Kadokura, Hiroshi, Imagawa, Yusuke, Inoue, Michihiro, Yanagitani, Kota, Kohno, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130286/
https://www.ncbi.nlm.nih.gov/pubmed/21398633
http://dx.doi.org/10.1093/nar/gkr132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130286/
https://www.ncbi.nlm.nih.gov/pubmed/21398633
http://dx.doi.org/10.1093/nar/gkr132

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