Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

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TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI nuclease, TALENs bind and cleave DNA in pairs. Binding specificity is determined by customizable arrays of polymorphic amino acid repeats in...

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Detalles Bibliográficos
Autores principales: Cermak, Tomas, Doyle, Erin L., Christian, Michelle, Wang, Li, Zhang, Yong, Schmidt, Clarice, Baller, Joshua A., Somia, Nikunj V., Bogdanove, Adam J., Voytas, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130291/
https://www.ncbi.nlm.nih.gov/pubmed/21493687
http://dx.doi.org/10.1093/nar/gkr218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130291/
https://www.ncbi.nlm.nih.gov/pubmed/21493687
http://dx.doi.org/10.1093/nar/gkr218

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