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Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics

Mammalian cells can decode the concentration of extracellular transforming growth factor-β (TGF-β) and transduce this cue into appropriate cell fate decisions. How variable TGF-β ligand doses quantitatively control intracellular signaling dynamics and how continuous ligand doses are translated into...

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Detalles Bibliográficos
Autores principales: Zi, Zhike, Feng, Zipei, Chapnick, Douglas A, Dahl, Markus, Deng, Difan, Klipp, Edda, Moustakas, Aristidis, Liu, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130555/
https://www.ncbi.nlm.nih.gov/pubmed/21613981
http://dx.doi.org/10.1038/msb.2011.22