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Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

BACKGROUND: Vpx is a virion-associated protein encoded by SIV(SM), a lentivirus endemic to the West African sooty mangabey (Cercocebus atys). HIV-2 and SIV(MAC), zoonoses resulting from SIV(SM )transmission to humans or Asian rhesus macaques (Macaca mulatta), also encode Vpx. In myeloid cells, Vpx p...

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Detalles Bibliográficos
Autores principales: Pertel, Thomas, Reinhard, Christian, Luban, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130655/
https://www.ncbi.nlm.nih.gov/pubmed/21696578
http://dx.doi.org/10.1186/1742-4690-8-49