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Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys

BACKGROUND: Granulocyte colony stimulating factor (G-CSF) regulates survival, proliferation, and differentiation of neutrophilic granulocyte precursors, Recombinant G-CSF has been used for the treatment of congenital and therapy-induced neutropenia and stem cell mobilization. Due to its intrinsic in...

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Detalles Bibliográficos
Autores principales: Jiang, Yongping, Jiang, Wenhong, Qiu, Yuchang, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130716/
https://www.ncbi.nlm.nih.gov/pubmed/21668998
http://dx.doi.org/10.1186/1756-8722-4-28