Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans

Chemotherapeutic agents are used in the treatment of many cancers, yet variable resistance and toxicities among individuals limit successful outcomes. Several studies have indicated outcome differences associated with ancestry among patients with various cancer types. Using both traditional SNP-base...

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Detalles Bibliográficos
Autores principales: Wheeler, Heather E., Gorsic, Lidija K., Welsh, Marleen, Stark, Amy L., Gamazon, Eric R., Cox, Nancy J., Dolan, M. Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130766/
https://www.ncbi.nlm.nih.gov/pubmed/21755009
http://dx.doi.org/10.1371/journal.pone.0021920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130766/
https://www.ncbi.nlm.nih.gov/pubmed/21755009
http://dx.doi.org/10.1371/journal.pone.0021920

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