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Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans
Chemotherapeutic agents are used in the treatment of many cancers, yet variable resistance and toxicities among individuals limit successful outcomes. Several studies have indicated outcome differences associated with ancestry among patients with various cancer types. Using both traditional SNP-base...
Autores principales: | Wheeler, Heather E., Gorsic, Lidija K., Welsh, Marleen, Stark, Amy L., Gamazon, Eric R., Cox, Nancy J., Dolan, M. Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130766/ https://www.ncbi.nlm.nih.gov/pubmed/21755009 http://dx.doi.org/10.1371/journal.pone.0021920 |
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