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Regulatory Domain Selectivity in the Cell-Type Specific PKN-Dependence of Cell Migration

The mammalian protein kinase N (PKN) family of Serine/Threonine kinases comprises three isoforms, which are targets for Rho family GTPases. Small GTPases are major regulators of the cellular cytoskeleton, generating interest in the role(s) of specific PKN isoforms in processes such as cell migration...

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Detalles Bibliográficos
Autores principales: Lachmann, Sylvie, Jevons, Amy, De Rycker, Manu, Casamassima, Adele, Radtke, Simone, Collazos, Alejandra, Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130767/
https://www.ncbi.nlm.nih.gov/pubmed/21754995
http://dx.doi.org/10.1371/journal.pone.0021732