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Similar NF-κB Gene Signatures in TNF-α Treated Human Endothelial Cells and Breast Tumor Biopsies

BACKGROUND: Endothelial dysfunction has been implicated in the pathogenesis of diverse pathologies ranging from vascular and immune diseases to cancer. TNF-α is one of the mediators of endothelial dysfunction through the activation of transcription factors, including NF-κB. While HUVEC (macrovascula...

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Detalles Bibliográficos
Autores principales: Perrot-Applanat, Martine, Vacher, Sophie, Toullec, Aurore, Pelaez, Irma, Velasco, Guillaume, Cormier, Françoise, Saad, Hanan El Sheikh, Lidereau, Rosette, Baud, Véronique, Bièche, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130773/
https://www.ncbi.nlm.nih.gov/pubmed/21754991
http://dx.doi.org/10.1371/journal.pone.0021589