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IgE-Mediated Enhancement of CD4(+) T Cell Responses in Mice Requires Antigen Presentation by CD11c(+) Cells and Not by B Cells

IgE antibodies, administered to mice together with their specific antigen, enhance antibody and CD4(+) T cell responses to this antigen. The effect is dependent on the low affinity receptor for IgE, CD23, and the receptor must be expressed on B cells. In vitro, IgE-antigen complexes are endocytosed...

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Detalles Bibliográficos
Autores principales: Henningsson, Frida, Ding, Zhoujie, Dahlin, Joakim S., Linkevicius, Marius, Carlsson, Fredrik, Grönvik, Kjell-Olov, Hallgren, Jenny, Heyman, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130775/
https://www.ncbi.nlm.nih.gov/pubmed/21765910
http://dx.doi.org/10.1371/journal.pone.0021760