Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity

BACKGROUND: K2 products are synthetic cannabinoid-laced, marijuana-like drugs of abuse, use of which is often associated with clinical symptoms atypical of marijuana use, including hypertension, agitation, hallucinations, psychosis, seizures and panic attacks. JWH-018, a prevalent K2 synthetic canna...

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Detalles Bibliográficos
Autores principales: Brents, Lisa K., Reichard, Emily E., Zimmerman, Sarah M., Moran, Jeffery H., Fantegrossi, William E., Prather, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130777/
https://www.ncbi.nlm.nih.gov/pubmed/21755008
http://dx.doi.org/10.1371/journal.pone.0021917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130777/
https://www.ncbi.nlm.nih.gov/pubmed/21755008
http://dx.doi.org/10.1371/journal.pone.0021917

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