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Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity
BACKGROUND: K2 products are synthetic cannabinoid-laced, marijuana-like drugs of abuse, use of which is often associated with clinical symptoms atypical of marijuana use, including hypertension, agitation, hallucinations, psychosis, seizures and panic attacks. JWH-018, a prevalent K2 synthetic canna...
Autores principales: | Brents, Lisa K., Reichard, Emily E., Zimmerman, Sarah M., Moran, Jeffery H., Fantegrossi, William E., Prather, Paul L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130777/ https://www.ncbi.nlm.nih.gov/pubmed/21755008 http://dx.doi.org/10.1371/journal.pone.0021917 |
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