Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma

BACKGROUND: Multiple myeloma (MM) is a disease of cell cycle dysregulation while cell cycle modulation can be a target for MM therapy. In this study we investigated the effects and mechanisms of action of a sesquiterpene lactone 6-O-angeloylplenolin (6-OAP) on MM cells. METHODOLOGY/PRINCIPAL FINDING...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Chen, Xiao-Qin, Liang, Heng-Xing, Zhang, Feng-Xiang, Zhang, Bo, Jin, Jie, Chen, Yong-Long, Cheng, Yong-Xian, Zhou, Guang-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130785/
https://www.ncbi.nlm.nih.gov/pubmed/21755010
http://dx.doi.org/10.1371/journal.pone.0021930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130785/
https://www.ncbi.nlm.nih.gov/pubmed/21755010
http://dx.doi.org/10.1371/journal.pone.0021930

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