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SFRS7-Mediated Splicing of Tau Exon 10 Is Directly Regulated by STOX1A in Glial Cells

BACKGROUND: In this study, we performed a genome-wide search for effector genes bound by STOX1A, a winged helix transcription factor recently demonstrated to be involved in late onset Alzheimer's disease and affecting the amyloid processing pathway. METHODOLOGY/PRINCIPAL FINDINGS: Our results s...

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Detalles Bibliográficos
Autores principales: van Abel, Daan, Hölzel, Dennis R., Jain, Shushant, Lun, Fiona M. F., Zheng, Yama W. L., Chen, Eric Z., Sun, Hao, Chiu, Rossa W. K., Lo, Y. M. Dennis, van Dijk, Marie, Oudejans, Cees B. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130792/
https://www.ncbi.nlm.nih.gov/pubmed/21755018
http://dx.doi.org/10.1371/journal.pone.0021994