Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction

We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich sc1 RNA. The bound RNA forms a novel G-quadruplex separated from the flanking duplex stem by a mixed juncti...

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Detalles Bibliográficos
Autores principales: Phan, Anh Tuân, Kuryavyi, Vitaly, Darnell, Jennifer C., Serganov, Alexander, Majumdar, Ananya, Ilin, Serge, Raslin, Tanya, Polonskaia, Anna, Chen, Cynthia, Clain, David, Darnell, Robert B., Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130835/
https://www.ncbi.nlm.nih.gov/pubmed/21642970
http://dx.doi.org/10.1038/nsmb.2064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130835/
https://www.ncbi.nlm.nih.gov/pubmed/21642970
http://dx.doi.org/10.1038/nsmb.2064

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