Integrating energy calculations with functional assays to decipher the specificity of G-protein inactivation by RGS proteins

The diverse RGS protein family is responsible for the precise timing of G-protein signaling. To understand how RGS protein structure encodes their common ability to inactivate G-proteins and their selective G-protein recognition, we integrated structure-based energy calculations with biochemical mea...

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Detalles Bibliográficos
Autores principales: Kosloff, Mickey, Travis, Amanda M., Bosch, Dustin E., Siderovski, David P., Arshavsky, Vadim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130846/
https://www.ncbi.nlm.nih.gov/pubmed/21685921
http://dx.doi.org/10.1038/nsmb.2068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130846/
https://www.ncbi.nlm.nih.gov/pubmed/21685921
http://dx.doi.org/10.1038/nsmb.2068

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