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Integrating energy calculations with functional assays to decipher the specificity of G-protein inactivation by RGS proteins
The diverse RGS protein family is responsible for the precise timing of G-protein signaling. To understand how RGS protein structure encodes their common ability to inactivate G-proteins and their selective G-protein recognition, we integrated structure-based energy calculations with biochemical mea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130846/ https://www.ncbi.nlm.nih.gov/pubmed/21685921 http://dx.doi.org/10.1038/nsmb.2068 |