Genetic Testing for Lynch Syndrome in Individuals Newly Diagnosed with Colorectal Cancer to Reduce Morbidity and Mortality from Colorectal Cancer in Their Relatives

Individuals with Lynch syndrome, sometimes referred to as hereditary non-polyposis colorectal cancer (HNPCC), have an increased risk of developing colorectal cancer (CRC) as well as other cancers. The increased risk is due to inherited mutations in mismatch repair (MMR) genes, which reduce the abili...

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Detalles Bibliográficos
Autores principales: Coates, Ralph, Williams, Marc, Melillo, Stephanie, Gudgeon, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Evidence on Genomic Tests
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130897/
https://www.ncbi.nlm.nih.gov/pubmed/21743847
http://dx.doi.org/10.1371/currents.RRN1246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130897/
https://www.ncbi.nlm.nih.gov/pubmed/21743847
http://dx.doi.org/10.1371/currents.RRN1246

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