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The impact of sample storage time on estimates of association in biomarker discovery studies

BACKGROUND: Using serum, plasma or tumor tissue specimens from biobanks for biomarker discovery studies is attractive as samples are often readily available. However, storage over longer periods of time can alter concentrations of proteins in those specimens. We therefore assessed the bias in estima...

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Detalles Bibliográficos
Autores principales: Kugler, Karl G, Hackl, Werner O, Mueller, Laurin AJ, Fiegl, Heidi, Graber, Armin, Pfeiffer, Ruth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131186/
https://www.ncbi.nlm.nih.gov/pubmed/21743835
http://dx.doi.org/10.1186/2043-9113-1-9