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The impact of sample storage time on estimates of association in biomarker discovery studies
BACKGROUND: Using serum, plasma or tumor tissue specimens from biobanks for biomarker discovery studies is attractive as samples are often readily available. However, storage over longer periods of time can alter concentrations of proteins in those specimens. We therefore assessed the bias in estima...
Autores principales: | Kugler, Karl G, Hackl, Werner O, Mueller, Laurin AJ, Fiegl, Heidi, Graber, Armin, Pfeiffer, Ruth M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131186/ https://www.ncbi.nlm.nih.gov/pubmed/21743835 http://dx.doi.org/10.1186/2043-9113-1-9 |
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