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Protein kinase Cα downregulation via siRNA-PKCα released from foldable capsular vitreous body in cultured human retinal pigment epithelium cells

We previously found that downregulation of protein kinase Cα (PKCα) can inhibit retinal pigment epithelium (RPE) cell proliferation involved in the development of proliferative vitreoretinopathy (PVR). In this study, we tested whether PKCα could be downregulated via small interfering RNA (siRNA)-PKC...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoqing, Liu, Yaqin, Jiang, Zhaoxin, Zhou, Lian, Ge, Jian, Gao, Qianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131196/
https://www.ncbi.nlm.nih.gov/pubmed/21753881
http://dx.doi.org/10.2147/IJN.S19405