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The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles

BACKGROUND: The process of HIV-1 genomic RNA (gRNA) encapsidation is governed by a number of viral encoded components, most notably the Gag protein and gRNA cis elements in the canonical packaging signal (ψ). Also implicated in encapsidation are cis determinants in the R, U5, and PBS (primer binding...

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Detalles Bibliográficos
Autores principales: Cockrell, Adam S, van Praag, Henriette, Santistevan, Nicholas, Ma, Hong, Kafri, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131246/
https://www.ncbi.nlm.nih.gov/pubmed/21702950
http://dx.doi.org/10.1186/1742-4690-8-51