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Physical Exercise Regulates p53 Activity Targeting SCO2 and Increases Mitochondrial COX Biogenesis in Cardiac Muscle with Age

The purpose of this study was to outline the timelines of mitochondrial function, oxidative stress and cytochrome c oxidase complex (COX) biogenesis in cardiac muscle with age, and to evaluate whether and how these age-related changes were attenuated by exercise. ICR/CD-1 mice were treated with pifi...

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Detalles Bibliográficos
Autores principales: Qi, Zhengtang, He, Jie, Su, Yuhui, He, Qiang, Liu, Jingxia, Yu, Lu, Al-Attas, Omar, Hussain, Tajamul, Ding, Shuzhe, Ji, Liu, Qian, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131270/
https://www.ncbi.nlm.nih.gov/pubmed/21750704
http://dx.doi.org/10.1371/journal.pone.0021140