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Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs

Reinitiation is a gene-specific translational control mechanism characterized by the ability of some short upstream uORFs to retain post-termination 40S subunits on mRNA. Its efficiency depends on surrounding cis-acting sequences, uORF elongation rates, various initiation factors, and the intercistr...

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Detalles Bibliográficos
Autores principales: Munzarová, Vanda, Pánek, Josef, Gunišová, Stanislava, Dányi, István, Szamecz, Béla, Valášek, Leoš Shivaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131280/
https://www.ncbi.nlm.nih.gov/pubmed/21750682
http://dx.doi.org/10.1371/journal.pgen.1002137