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Machupo Virus Glycoprotein Determinants for Human Transferrin Receptor 1 Binding and Cell Entry

Machupo virus (MACV) is a highly pathogenic New World arenavirus that causes hemorrhagic fever in humans. MACV, as well as other pathogenic New World arenaviruses, enter cells after their GP1 attachment glycoprotein binds to their cellular receptor, transferrin receptor 1 (TfR1). TfR1 residues essen...

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Detalles Bibliográficos
Autores principales: Radoshitzky, Sheli R., Longobardi, Lindsay E., Kuhn, Jens H., Retterer, Cary, Dong, Lian, Clester, Jeremiah C., Kota, Krishna, Carra, John, Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131282/
https://www.ncbi.nlm.nih.gov/pubmed/21750710
http://dx.doi.org/10.1371/journal.pone.0021398