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Identification of a Mutation Associated with Fatal Foal Immunodeficiency Syndrome in the Fell and Dales Pony

The Fell and Dales are rare native UK pony breeds at risk due to falling numbers, in-breeding, and inherited disease. Specifically, the lethal Mendelian recessive disease Foal Immunodeficiency Syndrome (FIS), which manifests as B-lymphocyte immunodeficiency and progressive anemia, is a substantial t...

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Detalles Bibliográficos
Autores principales: Fox-Clipsham, Laura Y., Carter, Stuart D., Goodhead, Ian, Hall, Neil, Knottenbelt, Derek C., May, Paul D. F., Ollier, William E., Swinburne, June E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131283/
https://www.ncbi.nlm.nih.gov/pubmed/21750681
http://dx.doi.org/10.1371/journal.pgen.1002133