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Efficient and Directive Generation of Two Distinct Endoderm Lineages from Human ESCs and iPSCs by Differentiation Stage-Specific SOX17 Transduction

The establishment of methods for directive differentiation from human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) is important for regenerative medicine. Although Sry-related HMG box 17 (SOX17) overexpression in ESCs leads to differentiation of either extraembryonic or def...

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Detalles Bibliográficos
Autores principales: Takayama, Kazuo, Inamura, Mitsuru, Kawabata, Kenji, Tashiro, Katsuhisa, Katayama, Kazufumi, Sakurai, Fuminori, Hayakawa, Takao, Furue, Miho Kusuda, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131299/
https://www.ncbi.nlm.nih.gov/pubmed/21760905
http://dx.doi.org/10.1371/journal.pone.0021780