TBP Binding-Induced Folding of the Glucocorticoid Receptor AF1 Domain Facilitates Its Interaction with Steroid Receptor Coactivator-1

The precise mechanism by which glucocorticoid receptor (GR) regulates the transcription of its target genes is largely unknown. This is, in part, due to the lack of structural and functional information about GR's N-terminal activation function domain, AF1. Like many steroid hormone receptors (...

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Detalles Bibliográficos
Autores principales: Khan, Shagufta H., Ling, Jun, Kumar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131385/
https://www.ncbi.nlm.nih.gov/pubmed/21760925
http://dx.doi.org/10.1371/journal.pone.0021939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131385/
https://www.ncbi.nlm.nih.gov/pubmed/21760925
http://dx.doi.org/10.1371/journal.pone.0021939

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