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Calcitonin receptor-mediated CFTR activation in human intestinal epithelial cells

High levels of calcitonin (CT) observed in medullary thyroid carcinoma and other CT-secreting tumours cause severe diarrhoea. Previous studies have suggested that CT induces active chloride secretion. However, the involvement of CT receptor (CTR) and the molecular mechanisms underlying the modulatio...

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Detalles Bibliográficos
Autores principales: Liu, Hongguang, Singla, Amika, Ao, Mei, Gill, Ravinder K, Venkatasubramanian, Jayashree, Rao, Mrinalini C, Alrefai, Waddah A, Dudeja, Pradeep K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131411/
https://www.ncbi.nlm.nih.gov/pubmed/21251218
http://dx.doi.org/10.1111/j.1582-4934.2011.01264.x