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Non-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death

β-catenin is constantly degraded through the ubiquitin-proteasomal pathway. We here report that a different type of β-catenin degradation is causally involved in epidermal cell death. We observed that reactive oxygen species (ROS) caused β-catenin degradation in the epidermal cells through a caspase...

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Detalles Bibliográficos
Autores principales: Omori, Emily, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131442/
https://www.ncbi.nlm.nih.gov/pubmed/21383695
http://dx.doi.org/10.1038/onc.2011.49